Table 5.

Risk of One or Multiple Nonmelanoma Skin Cancers on the Basis of MC1R Gene Variants

	One Skin Tumor		Two to Four Skin Tumors		Five or More Skin Tumors
	No. of Individuals with
Genotype or Comparison	Controls	Patients	Controls	Patients	Controls	Patients
WT/WT	137	69	137	30	137	8
WT/Var	174	112	174	73	174	20
Var/Var	74	69	74	48	74	24
	OR (95% CI)
WT/Var vs. WT/WT	1.28 (.86–1.89)		1.92 (1.15–3.19)		1.97 (.79–5.03)
Var/Var vs. WT/WT	1.85 (1.17–2.94)		2.96 (1.68–5.25)		5.55 (2.24–14.22)

^aWt = wild-type allele; Var = variant allele.