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T. gondii-specific serum IgG2a levels in ts-4-vaccinated CD4-deficient and B6 mice. B6 and CD4-deficient mice were immunized by i.p. injection of 2 × 104 ts-4 tachyzoites and bled 8 weeks later. T. gondii-specific serum IgG2a titers were determined by ELISA. Antibody titers in immunized B6 mice were significantly (P < 0.05) higher than those in immunized CD4-deficient mice. Titers in unimmunized mice of both strains were beneath the limit of detection (log10 titer of 1.70).
