Table 2.

Estimated sensitivity and specificity of HSV-2 tests

	Focus	Biokit	Focus Plus Biokit
Sensitivity	99.2 (96.3,100.0)	90.5 (86.1,94.0)	99.1 (96,100.0)
Specificity	93.2 (91.8,94.6)	98.4 (97.5,99.3)	98.7 (98.1,99.4)
Positive Predictive Value	80.5 (76.9,84.2)	94.5 (90.5,97.3)	95.6 (93.4,97.8)
Negative Predictive Value	99.7 (98.9,100.0)	97.5 (96.6,98.4)	99.7 (98.9,100.0)

Ranges indicated show the confidence intervals for accuracy; these also incorporate the uncertainty from having confirmed only a portion of Focus negatives. Biokit was used to confirm all sera that were initially positive for HSV-2 antibodies by Focus HSV-2 ELISA; the combined test results are shown in the "Focus Plus Biokit" column.