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. 2005 Oct 21;102(44):15827–15832. doi: 10.1073/pnas.0505554102

Table 1. In vivo antiinflammatory effects of CpdA in a zymosan-induced inflamed paw mouse model.

Group Pretreatment Difference zymosan–PBS P value compared with PBS group P value compared with ethanol group P value DEX compared with CpdA group
1 PBS 2.02 ± 0.30 0.381 (NS)
2 Ethanol 1.89 ± 0.23 0.381 (NS)
3 DEX 1.20 ± 0.39 0.0009 (***) 0.0017 (**)
4 CpdA 1.07 ± 0.42 0.0004 (***) 0.0007 (***) 0.5596 (NS)

Mice were injected s.c. with zymosan in the footpad, and swelling was determined at 24 h after the injection. Pretreatment with CpdA, DEX, or solvent was for 30 min. Means ± SD were compared with a Student t test. ** and ***, 0.001 ≤ P < 0.01 and P < 0.001, respectively. NS, not significant.