FIG. 6.

Infection of HUVEC with a P. gingivalis fimA mutant does not stimulate ICAM-1 and VCAM-1 expression. HUVEC were infected with P. gingivalis strains 381 and DPG3 (fimA); cells harvested at 2, 24, and 48 h postinfection and processed for FACS analysis for ICAM-1 (A) and VCAM-1 (B). For uninfected HUVEC (black bars), HUVEC infected with P. gingivalis strain 381 (gray bars), and HUVEC infected with P. gingivalis strain DPG3 (open bars), values are the means ± standard errors of the means for three independent experiments. Statistical significance was assigned when the P value was <0.05 (*) or <0.001 (**) compared to uninfected HUVEC.