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. 2025 Nov 25;26:5. doi: 10.1186/s12890-025-04042-9

Table 2.

Docking results of IL-6 with four natural active ingredients

Target Active ingredient PubChem ID Binding energy (kcal/mol) Potential candidate
IL-6 Atractylenolide I 5,321,018 −7.50 Yes
Morphine 5,288,826 −7.18 No
Melanin 6,325,610 −7.12 No
Sophocarpine 115,269 −7.03 Yes