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. Author manuscript; available in PMC: 2026 Jan 4.
Published in final edited form as: Mod Pathol. 2024 Oct 9;38(1):100629. doi: 10.1016/j.modpat.2024.100629

Figure 2:

Figure 2:

High-grade serous carcinoma and serous borderline tumor arising from ovarian cystadenoma. (A) Photomicrographs from Case 1 illustrate the juxtaposition between the serous borderline tumor (SBT) and high-grade serous carcinoma (HGSC) components.

Immunohistochemical stains show WT1 and p53 expression patterns. (B) Copy number profiles of SBT and HGSC components. (C) Phylogenetic tree constructed based on mutations and LOH events. Truncal mutations are highlighted in red and pathogenic driver alterations are indicated. SNV - single nucleotide variants; DEL – deletion; INS – insertion; LOH – loss-of-heterozygosity.