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Urease activity in gastric homogenates from mice colonized by wild-type H. pylori strain M6 and colonizing mutants, compared to baseline. Results are expressed as the change in A340 over 2 h (see text). All mutant strains are significantly different from M6. Activities of strains M6(cag9-ureB), M6ΔureB(cag15-ureB), M6ΔureB(cag25-ureB), and M6ΔureB(hpn-ureB) are significantly greater than those of uninfected gastric homogenate (none) (P < 0.05).
