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. 2025 Dec 5;17(12):e98506. doi: 10.7759/cureus.98506

Table 3. Univariate analysis of the characteristics of the MD-IPMN cases with FPPA and those with UPA.

MD-IPMNs: main duct intraductal papillary mucinous neoplasms of the pancreas; FPPA: focal pancreatic parenchymal atrophy; UPA: upper pancreatic atrophy; AMY: serum amylase levels; LIP: serum lipase levels; CA19-9: serum carbohydrate antigen 19-9 levels; CEA: serum carcinoembryonic antigen levels; Ph: pancreatic head; Pbt: pancreatic body and tail; MPD: main pancreatic duct; MN: mural nodule.

*Student's t-test; **Fisher's exact test; ***Mann-Whitney U test. P <0.05 was considered statistically significant.

  FPPA (n = 4) UPA (n = 12) P-value
Age, mean ± SD, year* 72 ± 11 70 ± 6 0.752
Sex (male:female), n** 1:3 7:5 0.569
Symptoms, n (%)** 1 (25) 2 (17) 1.000
Diabetes mellitus, n (%)** 3 (75) 3 (25) 0.118
History of acute pancreatitis, n (%)** 1 (25) 2 (17) 1.000
Laboratory data      
AMY, median (range), IU/L, (n = 4/11)*** 61 (46–140) 60 (44–144) 1.000
LIP, median (range), IU/L, (n = 1/6)*** 150 45 (23–129) 0.286
CA19-9, median (range), U/mL, (n = 4/11)*** 15.4 (2.1–133) 3.8 (2.1–11) 0.114
CEA, median (range), ng/mL, (n = 4/11)*** 2.7 (1.4–25) 2.3 (1.2–41) 0.647
Image findings      
Location (Ph:Pbt), n** 3:1 4:8 0.262
Diameter of MPD, median (range), mm*** 6 (3–8) 11 (7–24) 0.017
Diameter of MPD < 7 mm, n (%)** 3 (75) 0 0.007
Height of MN, median (range), mm*** 3 (0–6) 7 (2–15) 0.074
Pathological findings      
Diagnosis (benign:malignant), n** 2:2 4:8 0.604
Histological subtype (gastric:non-gastric), (n = 4/11)** 2:2 5:6 1.000