Table 3. Univariate analysis of the characteristics of the MD-IPMN cases with FPPA and those with UPA.
MD-IPMNs: main duct intraductal papillary mucinous neoplasms of the pancreas; FPPA: focal pancreatic parenchymal atrophy; UPA: upper pancreatic atrophy; AMY: serum amylase levels; LIP: serum lipase levels; CA19-9: serum carbohydrate antigen 19-9 levels; CEA: serum carcinoembryonic antigen levels; Ph: pancreatic head; Pbt: pancreatic body and tail; MPD: main pancreatic duct; MN: mural nodule.
*Student's t-test; **Fisher's exact test; ***Mann-Whitney U test. P <0.05 was considered statistically significant.
| FPPA (n = 4) | UPA (n = 12) | P-value | |
| Age, mean ± SD, year* | 72 ± 11 | 70 ± 6 | 0.752 |
| Sex (male:female), n** | 1:3 | 7:5 | 0.569 |
| Symptoms, n (%)** | 1 (25) | 2 (17) | 1.000 |
| Diabetes mellitus, n (%)** | 3 (75) | 3 (25) | 0.118 |
| History of acute pancreatitis, n (%)** | 1 (25) | 2 (17) | 1.000 |
| Laboratory data | |||
| AMY, median (range), IU/L, (n = 4/11)*** | 61 (46–140) | 60 (44–144) | 1.000 |
| LIP, median (range), IU/L, (n = 1/6)*** | 150 | 45 (23–129) | 0.286 |
| CA19-9, median (range), U/mL, (n = 4/11)*** | 15.4 (2.1–133) | 3.8 (2.1–11) | 0.114 |
| CEA, median (range), ng/mL, (n = 4/11)*** | 2.7 (1.4–25) | 2.3 (1.2–41) | 0.647 |
| Image findings | |||
| Location (Ph:Pbt), n** | 3:1 | 4:8 | 0.262 |
| Diameter of MPD, median (range), mm*** | 6 (3–8) | 11 (7–24) | 0.017 |
| Diameter of MPD < 7 mm, n (%)** | 3 (75) | 0 | 0.007 |
| Height of MN, median (range), mm*** | 3 (0–6) | 7 (2–15) | 0.074 |
| Pathological findings | |||
| Diagnosis (benign:malignant), n** | 2:2 | 4:8 | 0.604 |
| Histological subtype (gastric:non-gastric), (n = 4/11)** | 2:2 | 5:6 | 1.000 |