TABLE 3.
Coinfection of C57BL/6j and BALB/c mice with wild-type and nixA strains of H. pylori SS1 at 5 weeks postinfection
| Mouse strain | Groupa | Colony countsb on plates without kanamycin
|
Colony countsb on plates with kanamycin
|
||
|---|---|---|---|---|---|
| Log10 CFU/g (mean ± SD) | No. of mice colonized/totalc | Log10 CFU/g (mean ± SD) | No. of mice colonized/total | ||
| C57BL/6j | Control | 0∗ | 0/5 | 0∗ | 0/5 |
| SS1 | 6.7 ± 0.2 | 10/10 | 0∗ | 0/10 | |
| nixA | NA | NA | 6.4 ± 0.4 | 10/10 | |
| SS1 + nixA | 6.5 ± 0.3 | 9/9 | 0∗ | 0/9 | |
| BALB/c | Control | 0∗ | 0/5 | 0∗ | 0/5 |
| SS1 | 5.8 ± 0.3 | 10/10 | 0∗ | 0/0 | |
| nixA | NA | NA | 4.8 ± 0.7 | 10/10 | |
| SS1 + nixA | 5.4 ± 0.7 | 10/10 | 0∗ | 0/0 | |
a
Mice were inoculated with sterile BHI broth (negative control) or ∼108 CFU of either SS1 or the nixA strain or both SS1 and the nixA strain.
b
Values are means and standard deviations calculated for infected mice only. NA, not applicable. ∗, no colonies were recovered; below limit of detection (102 to 103 CFU/g).
c
Proportion of mice colonized was determined by viable-colony counts.