Table 1. Characteristics of patient population.
| Factor | Group | PD | SD/PR | P* |
|---|---|---|---|---|
| Total sample size | 34 | 14 (41) | 20 (59) | |
| Age, years | >0.1† | |||
| Median | 54 (20-75) | 55 (20-73) | 51 (23-75) | |
| Gender | >0.1‡ | |||
| Male | 13 (38) | 9 (45) | 4 (29) | |
| Female | 21 (62) | 11 (55) | 10 (71) | |
| Pathology | >0.1‡ | |||
| WHO grade III | 7 (21) | 3 (21) | 4 (20) | |
| WHO grade IV | 27 (79) | 11 (79) | 16 (80) | |
| Karnofsky performance status | >0.1‡ | |||
| ≥70 | 24 (71) | 11 (79) | 13 (65) | |
| <70 | 10 (29) | 3 (21) | 7 (35) | |
| Surgery | 0.09‡ | |||
| Biopsy | 17 (50) | 10 (71) | 7 (35) | |
| Surgical resection | 17 (50) | 4 (29) | 13 (65) | |
| Tumor location | >0.1‡ | |||
| Frontal | 10 (29) | 3 (21) | 7 (35) | |
| Parietal | 8 (24) | 3 (21) | 5 (25) | |
| Temporal | 9 (26) | 4 (29) | 5 (29) | |
| Thalamic | 6 (18) | 4 (29) | 2 (10) | |
| Multifocal | 1 (3) | 1 (5) | ||
| Radiation therapy | >0.1‡ | |||
| Yes | 33 (97) | 13 (93) | 20 (100) | |
| No | 1 (3) | 1 (7) | ||
| Median dose, Gy | 70 (0-75) | 70 (0-75) | 70 (36-75) | >0.1† |
| Chemotherapy | >0.1‡ | |||
| Yes | 29 (85) | 13 (93) | 16 (80) | |
| No | 5 (15) | 1 (7) | 4 (20) | |
| Concurrent TMZ/XRT | 8 (24) | 2 (14) | 6 (30) | >0.1‡ |
| Any TMZ | 28 (82) | 12 (86) | 16 (80) |
Entries are number (and range or percentage) in each category. TMZ, temozolomide; XRT, radiation therapy.
*
P refers to the differences between the columns SD/PR and PD.
†
Student's t test.
‡
Fisher's exact test.