TABLE 2.
| Symptom | No. of patients with subjective complaints and grade of complaint (X = 42) after dose:
|
||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1
|
2
|
3
|
4 (group 3 only)
|
||||||||||||||
| 1+ | 2+ | 3+ | 4+ | 1+ | 2+ | 3+ | 4+ | 1+ | 2+ | 3+ | 4+ | 1+ | 2+ | 3+ | 4+ | ||
| Fatigue | 4 | 4 | 4 | 4 | 1 | 1 | 1 | 1 | |||||||||
| Headache | 2 | 4 | 2 | 2 | 1 | 1 | 3 | ||||||||||
| Muscle aches | 3 | 1 | 1 | 1 | 1 | ||||||||||||
| Runny nose | 4 | 2 | 1 | 1 | 2 | 1 | |||||||||||
| Nasal discharge; stuffiness | 2 | 1 | 2 | 1 | 4 | 1 | |||||||||||
| Sore throat | 1 | 1 | 1 | 1 | |||||||||||||
| Cough | 2 | 1 | 1 | 1 | 1 | ||||||||||||
| Nasal sting-burn | 1 | ||||||||||||||||
| Nasal itch | 2 | ||||||||||||||||
| Nosebleed | |||||||||||||||||
| Postnasal drip | 1 | 4 | |||||||||||||||
a
One patient had a 99.7°F fever after dose 1. One patient had a 100°F fever after dose 2.
b
Shown are reported side effects per dosing day for all 42 volunteers. The scoring system is described in “Adverse reactions.”