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. 2005 Oct 25;391(Pt 3):549–560. doi: 10.1042/BJ20050296

Figure 3. Proteins that bind/transport bile acids across bile canaliculus and basolateral membranes of L-FABP wild-type (+/+) and L-FABP (−/−) mice.

Figure 3

Proteins from liver homogenates of male mice were separated by SDS/PAGE, electroblotted on to nitrocellulose membranes, and incubated with polyclonal antisera directed against canalicular bile salt translocase proteins such as BSEP (A) and MRP2 (B), or against basolateral/serosal bile salt translocase protein such as OATP-1 (C) as described in the Experimental section. The amount of protein is expressed in arbitrary units with that present in the control-fed L-FABP (+/+) liver homogenates defined to be 1. The data represent the means±S.E.M. For L-FABP (−/−) versus L-FABP (+/+): *, P<0.05; **, P<0.01; ***, P<0.001. For cholesterol diet versus control diet, ###, P<0.001.