Figure 1. Sequence of the 5′-flanking region of the human PiC gene.

The nucleotides preceding the transcription start site (boxed G at position +1) are indicated by negative numbers. The Sp1 and CREB binding sites and the silencer region (WT) are represented in italics and underlined. Boxed nucleotide sequences indicate the forward (F1–F7) and reverse (REV) primers employed to generate a series of deletion fragments. The translational start codon ATG is also underlined.