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. 2026 Jan 6;13:3. doi: 10.1186/s40662-025-00471-z

Table 2.

Comparison of intraocular pressure and Singapore I Vessel Assessment (SIVA) measures of retinal blood vessels between the sitting position and supine position

Variable Healthy control (n = 58) Participants with DM (n = 50)
Sitting Supine P value* Sitting Supine P value*
Mean ± SE Mean ± SE Mean ± SE Mean ± SE
Intraocular pressure (mmHg) 15.1 ± 0.3 16.8 ± 0.4 <0.001 15.8 ± 0.37 17.8 ± 0.37 <0.001
Retinal arteriolar caliber (µm) 92.48 ± 3.48 89.32 ± 3.00 0.049 111.55 ± 5.93 114.69 ± 6.17 0.104
Retinal venular caliber (µm) 130.19 ± 4.89 124.89 ± 4.40 0.027 160.84 ± 6.594 161.89 ± 8.28 0.880
Retinal arteriolar fractal dimension 1.199 ± 0.006 1.196 ± 0.006 0.107 1.169 ± 0.006 1.166 ± 0.007 0.169
Retinal venular fractal dimension 1.199 ± 0.006 1.193 ± 0.005 0.003 1.179 ± 0.006 1.173 ± 0.007 0.013
Retinal arteriolar simple tortuosity 1.081 ± 0.001 1.080 ± 0.001 0.162 1.081 ± 0.002 1.085 ± 0.002 0.051
Retinal venular simple tortuosity 1.091 ± 0.002 1.089 ± 0.002 0.371 1.090 ± 0.002 1.090 ± 0.002 0.773
Retinal arteriolar curvature tortuosity (×104) 2.611 ± 0.132 2.720 ± 0.134 0.224 2.112 ± 0.198 2.005 ± 0.195 0.238
Retinal venular curvature tortuosity (×104) 3.125 ± 0.163 3.181 ± 0.155 0.574 2.581 ± 0.261 2.432 ± 0.237 0.147
Arteriolar branching angle (degrees) 68.17 ± 1.38 68.68 ± 2.33 0.810 69.71 ± 2.90 68.61 ± 2.11 0.720
Venular branching angle (degrees) 72.58 ± 2.14 70.76 ± 2.34 0.310 72.73 ± 1.43 72.01 ± 1.77 0.828

DM = diabetes mellitus; SE = standard error

* Represents paired t-test. P values in bold indicate statistical significance