FIG. 5.

CneF-injected sponges in mice immunized with the protective immunogen, CneF-CFA, contain significantly higher concentrations of NO than CneF-injected sponges in mice immunized with the nonprotective immunogen, HKC-CFA. The experimental design was the same as that described in the Fig. 1 legend. The sponges were removed 24 h after injection with CneF or saline, and the fluid was collected from each sponge for nitrite measurements. Where there are significant differences, bars indicate the groups compared. The P values are shown above the bars.