FIG. 7.

Supernatant-induced, B-cell FasL expression is inhibited by anti-IL-4 and anti-IL-10 antibodies. Culture supernatants from SEA-stimulated splenocytes of mice infected for 8 weeks were pretreated for 30 min with 10-μg/ml concentrations of the indicated neutralizing antibodies prior to 20 h of culture with magnetic-bead-purified CD19⁺ B cells. FasL expression was evaluated by two-color flow cytometry as for Fig. 6. Ratios of MFI ± standard deviations of triplicate samples compared to those of anti-DNP control antibody (∗) are plotted. Data are from a representative of three experiments.