TABLE 4.
Summary of positive immunological responses which developed following M. bovis challenge in calves depleted and not depleted of WC1+ γδ T cells
| Animal | Maximum response index (fold increase)c
|
||||||
|---|---|---|---|---|---|---|---|
| LPA | IL-2 | IFN-γ | IL-4 | IgM | IgG1 | IgG2 | |
| Da | 11 | 8 | 11 | 6 | 9 | ||
| D | 8 | 5 | 9 | 4 | 16 | 10 | |
| D | 28 | 9 | 10 | 2 | |||
| D | 69 | 5 | 12 | 7 | 18 | 6 | |
| D | 15 | 3 | 10 | 4 | 15 | ||
| D | 100 | 2 | 11 | 7 | 4 | ||
| NDb | 6 | 2 | 3 | 11 | |||
| ND | 13 | 6 | 8 | 18 | |||
| ND | 29 | 2 | 6 | 8 | 9 | 10 | |
| ND | 67 | 2 | 11 | 25 | 10 | ||
| ND | 27 | 6 | 10 | 3 | 9 | 10 | 25 |
| ND | 28 | 13 | 11 | 3 | 13 | ||
a
Depleted animal.
b
Nondepleted animal.
c
For each animal, when positive immune responses were detected postinfection, the maximum response index (fold increase) is given. Cutoffs and calculation of indices are defined in Materials and Methods.