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. 2025 Dec 31;16:624. doi: 10.1038/s41598-025-31771-y

Table 8.

Correlation of MPO and CIT-HIST-H3 with other parameters studied among the sepsis patients.

Parameters MPO (ng/ml) CIT-HIST-H3 (ng/ml)
r P-value r P-value
MPO (ng/ml) 0.244* 0.044
CIT-HIST-H3 (ng/ml) 0.244* 0.044 s
Age (years) 0.334** 0.005 0.108 0.376
HB g/dL – 0.032 0.795 – 0.150 0.218
WBCs (x103/ul) – 0.053 0.663 0.066 0.587
PNL (x103/ul) 0.128 0.293 0.251* 0.037
LYMP (x103/ul) – 0.231 0.056 – 0.371** 0.002
N/L ratio 0.258* 0.032 0.441** 0.000
PLTs (x103/ul) – 0.179 0.140 – 0.334** 0.005
PT (sec) 0.207 0.087 0.246* 0.042
INR 0.160 0.190 0.326** 0.006
PTT (sec) 0.150 0.234 0.249* 0.045
FDPs (< 5 Ug/ml) 0.195 0.108 0.233 0.054
D dimer (0-0.55 Ug/ml) 0.211 0.134 0.260 0.062
Fibrinogen (2–4 g/L) -0.258* 0.035 – 0.294* 0.016
Procalcitonin (up to 0.05 ng/ml) – 0.188 0.259 -0.104 0.534
CRP (< 5 mg/L) – 0.115 0.410 -0.172 0.212
Creatinine mg/dl 0.214* 0.014 0.162 0.064
Total Bilirubin mg/dl 0.188* 0.027 0.124 0.149
PAI (N = 5-20ng/ml) 0.501** 0.000 0.249* 0.039
SOFA score – 0.017 0.887 – 0.077 0.530
JAAM2 DIC score ≥ 3 0.293* 0.015 0.432** 0.000

P-value > 0.05: Non-significant; *P-value < 0.05: Significant; **P-value < 0.01: Highly significant. Spearman correlation coefficient.