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. 2026 Jan 1;16(6):2952–2983. doi: 10.7150/thno.124189

Figure 3.

Figure 3

In vivo pharmacokinetic analysis of ATV/DTX. Profiles of venous plasma concentrations of ATV and DTX in rats following (A) a single IV administration of 2.5 mg/kg ATV (ATV-IV), (B) oral administration of an aqueous dispersion of 2.5 mg/kg ATV (ATV-oral) or MCT-NE#9 (equivalent to 2.5 mg/kg of ATV), (C) a single IV administration of 10 mg/kg DTX (DTX-IV), and (D) oral administration of an aqueous dispersion of 10 mg/kg DTX (DTX-oral) or MCT-NE#9 (equivalent to 10 mg/kg of DTX). Values are shown as mean ± SD (n = 4).