Table 5.
Univariable analysis of factors associated with complete recovery
| Variables | OR (95% CI)a | P Value |
|---|---|---|
| Age at biopsyb | 1.03 (0.96 to 1.11) | 0.43 |
| Male | 0.44 (0.10 to 1.76) | 0.24 |
| Prior diagnosis of sarcoidosis | 1.09 (0.24 to 4.47) | 0.91 |
| Renal-limited sarcoidosis | 1.43 (0.18 to 29.72) | 0.76 |
| Comorbidity | 1.26 (0.28 to 5.22) | 0.76 |
| Baseline sCr (mg/dl)b | 0.75 (0.33 to 1.75) | 0.48 |
| sCr at biopsy (mg/dl)b | 0.49 (0.27 to 0.75) | 0.001c |
| sCr at biopsy ≥2.4 mg/dl (versus <2.4 mg/dl) | 0.17 (0.02 to 0.80) | 0.024c |
| 24 h proteinuria (g/24 h)b | 0.86 (0.49 to 1.54) | 0.55 |
| Baseline CKD | 0.55 (0.07 to 2.74) | 0.48 |
| AKI on CKD (versus AKI) | 0.78 (0.14 to 4.39) | 0.77 |
| AKI on CKD (versus CKD) | 0.38 (0.06 to 2.15) | 0.27 |
| Kidney stone | 0.62 (0.13 to 3.43) | 0.56 |
| Corrected calcium (mg/dl)b | 1.20 (0.80 to 1.95) | 0.39 |
| Hypercalcemia | 2.04 (0.43 to 9.04) | 0.35 |
| 25-hydroxy vitamin D (ng/ml)b | 0.97 (0.90 to 1.04) | 0.31 |
| 1,25-dihydroxy vitamin D (pg/dl)b | 1.04 (1.00 to 1.10) | 0.025c |
| Serum ACE (U/L)b | 1.00 (0.98 to 1.03) | 0.67 |
| Serum PTH (pg/ml)b | 0.98 (0.96 to 1.01) | 0.12 |
| Microscopic hematuria | 1.11 (0.12 to 23.90) | 0.93 |
| Sterile pyuria | 1.25 (0.21 to 8.64) | 0.89 |
| Glycosuria | 0.71 (0.06 to 16.33) | 0.79 |
| GIN | 0.28 (0.06 to 1.15) | 0.07 |
| Calcium phosphate deposits | 3.34 (0.83 to 15.22) | 0.09 |
| Moderate/severe IFTA | 0.14 (0.02 to 0.71) | 0.017c |
| Steroid use | 8.57 (1.40 to 71.70) | 0.021c |
| Sarcoidosis flares | 3.33 (0.51 to 65.99) | 0.23 |
ACE, angiotensin-converting enzyme; CI, confidence interval; GIN, granulomatous interstitial nephritis; IFTA, interstitial fibrosis and tubular atrophy; OR, odds ratio; PTH, parathyroid hormone; sCr, serum creatinine.
Odds ratio with 95% confidence interval and P values were calculated using logistic regression model.
Odds ratio is per unit change in regression.
P < 0.05.