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. 2026 Jan 8;38(1):4. doi: 10.1007/s44445-025-00102-2

Table 1.

Comparison of MOOKP and Boston KPro

Feature MOOKP (Modified Osteo-Odonto-Keratoprosthesis) Boston KPro
Structure & Materials Biological (dental lamina with dentin, bone, PMMA optical cylinder) Biocompatible (PMMA, titanium in Type II)
Application Extreme cases (SJS, chemical burns, autoimmune diseases) Type I: Maintains a moist ocular environment; Type II: Designed for dry ocular surfaces
Surgical Procedure Multi-stage (2–3 stages over months); requires autograft Single-stage (mainly Type I), simpler and faster
Complications Lamina resorption (14%), mucosal necrosis, glaucoma (11.5%), retinal detachment (10%) Glaucoma (66%), retroprosthetic membrane formation (up to 17%), corneal melt (19%) (Wróblewska-Czajka et al. 2024)
Visual Outcomes 78% of patients achieve ≥ 20/400; better long-term stability Type I: 46.81% achieve ≥ 20/200 within 3 years (Wróblewska-Czajka et al. 2024); Type II: 50–58.6% after 5 years
Availability 14 centers worldwide, requires a multidisciplinary team More widely available, less infrastructure-dependent
Advantages Higher tolerance for extreme ocular surface damage Easier and faster to perform; more accessible
Disadvantages More complex, higher risk of complications (Ortiz-Morales et al. 2022) Shorter durability in harsh conditions, higher risk of retroprosthetic membranes

The table summarizes the key differences between MOOKP and Boston KPro, indicating their applications, results, and limitations