TABLE 3.

Bacterial loads in MF1 mice 24 h post-intranasal infection with 10⁶ CFU of S. pneumoniae following pulmonary TNF-α neutralization (n = 5 mice)

Treatment	Bacterial load (log CFU/ml) (mean ± SEM) in:
	Lung airways	Lung tissue	Bloodstream
Goat IgG	4.42 ± 0.19	5.04 ± 0.27	6.02 ± 0.37
anti-TNF-α	5.74 ± 0.03a	6.03 ± 0.23a	6.62 ± 0.45

^aP < 0.01 (higher for anti-TNF treatment than for goat IgG treatment).