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. 2025 Dec 30;37(6):912–928. doi: 10.21147/j.issn.1000-9604.2025.06.04

Table 3. Estimate changes in age-standardized 5-year relative survival by cancer types between 2003 and 2021.

Cancer sites Age-standardized 5-year relative
survival [% (95% CI)]
Average change per calendar
period [% (95% CI)]c
P for trendc
2003−2005a 2019−2021b
a, Data extracted from Table 3 in Reference (9); b, Data extracted from Table 2 in Reference (8); c, Data extracted from Supplementary Table 5 in Reference (8). 95% CI, 95% confidence interval.
Lip, oral cavity & pharynx 42.2 (38.9, 45.5) 47.0 (46.3, 47.7) 0.8 (−0.8, 2.4) 0.235
Nasopharynx 43.8 (39.6, 48.0) 56.2 (55.6, 56.9) 0.9 (−0.5, 2.4) 0.153
Esophagus 20.9 (20.1, 21.6) 27.9 (27.5, 28.2) 1.8 (0.5, 3.2) 0.019
Stomach 27.4 (26.7, 28.1) 35.2 (35.0, 35.4) 2.0 (1.4, 2.5) <0.001
Colon-rectum 47.2 (46.1, 48.3) 55.7 (55.4, 55.9) 2.3 (1.5, 3.1) 0.001
Liver 10.1 (9.5, 10.7) 14.4 (14.2, 14.5) 1.4 (0.6, 2.2) 0.009
Gallbladder 20.1 (18.1, 22.1) 17.8 (17.4, 18.3) −0.1 (−1.1, 1.0) 0.855
Pancreas 11.7 (10.5, 12.9) 8.5 (8.2, 8.7) −0.7 (−1.3, −0.1) 0.026
Larynx 51.7 (47.3, 56.1) 52.9 (51.8, 53.9) 1.5 (0.8, 2.1) 0.004
Lung 16.1 (15.6, 16.6) 28.7 (28.6, 28.9) 3.7 (1.4, 5.9) 0.010
Other thoracic organs 30.5 (25.0, 36.0) 40.1 (38.9, 41.4) 1.7 (0.5, 2.9) 0.019
Bone 17.1 (13.8, 20.5) 39.5 (38.6, 40.4) 3.9 (2.4, 5.4) 0.002
Melanoma of skin 38.8 (30.8, 46.7) 50.3 (48.6, 52.1) 4.2 (1.8, 6.6) 0.008
Breast 73.1 (71.2, 75.0) 80.9 (80.5, 81.3) 2.1 (1.4, 2.8) 0.001
Cervix 45.4 (40.7, 50.2) 66.9 (66.5, 67.4) 1.7 (−0.4, 3.8) 0.091
Uterus 55.1 (51.6, 58.5) 68.1 (67.2, 68.9) 3.5 (1.7, 5.3) 0.006
Ovary 38.9 (35.4, 42.3) 39.6 (38.9, 40.3) 0.3 (−0.2, 0.8) 0.132
Prostate 53.8 (49.5, 58.2) 71.1 (70.2, 71.9) 5.0 (3.4, 6.7) 0.001
Testis 48.0 (31.8, 64.2) 80.7 (78.7, 82.6) 2.7 (0.8, 4.7) 0.017
Kidney 62.0 (59.6, 64.4) 65.2 (64.6, 65.7) 1.9 (1.0, 2.7) 0.004
Bladder 67.3 (65.3, 69.4) 71.5 (71.0, 72.0) 1.6 (1.3, 1.9) <0.001
Brain 18.2 (16.0, 20.4) 37.7 (37.3, 38.2) 1.9 (0.3, 3.4) 0.029
Thyroid 67.5 (63.3, 71.8) 92.9 (92.4, 93.3) 2.8 (1.7, 3.9) 0.002
Lymphoma 32.6 (30.6, 34.6) 40.8 (40.4, 41.3) 1.9 (1.3, 2.4) 0.001
Leukemia 19.6 (17.6, 21.7) 30.6 (30.2, 31.1) 2.0 (0.7, 3.4) 0.014
All others 44.9 (43.2, 46.7) 52.2 (51.8, 52.6) 1.4 (0.2, 2.6) 0.035
All 30.9 (30.6, 31.2) 43.7 (43.6, 43.7) 3.4 (2.8, 4.0) <0.001