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. 2002 Mar;70(3):1287–1292. doi: 10.1128/IAI.70.3.1287-1292.2002

FIG. 3.

FIG. 3.

Effects of anti-Fn polyclonal antibodies and MAbs on in vitro attachment of M. tuberculosis to AMs. Fn-enhanced attachment of M. tuberculosis to AMs was examined in the presence of Fn and in the presence or absence of anti-Fn polyclonal antibodies and MAbs directed against the CBD, HBD, and GBD of Fn. Anti-Fn polyclonal antibody significantly decreased the Fn-enhanced attachment of M. tuberculosis to AMs (P < 0.05). Addition of a MAb specific to either CBD or HBD significantly decreased the attachment of M. tuberculosis to AMs (P < 0.05), whereas MAbs specific to GBD showed no effect on attachment of M. tuberculosis to AMs. Results are expressed as means + SEMs (error bars) of three experiments performed in triplicate.