TABLE 1.
Response to inoculation of H. ducreyi
| Subjecta | No. of days of observation | Isolate | No. of initial papules | Final outcome after initial papule formation
|
||
|---|---|---|---|---|---|---|
| No. of papules | No. of pustules | No. resolved | ||||
| 186 | 6 | 35000HP | 2 | 2 | ||
| 35000HP-sodC-cat | 1 | 1 | ||||
| 187 | 9 | 35000HP | 2 | 2 | ||
| 35000HP-sodC-cat | 3 | 3 | ||||
| 188 | 9 | 35000HP | 2 | 1 | 1 | |
| 35000HP-sodC-cat | 3 | 1 | 2 | |||
| 190 | 10 | 35000HP | 2 | 1 | 1 | |
| 35000HP-sodC-cat | 3 | 2 | 1 | |||
| 191 | 7 | 35000HP | 2 | 1 | 1 | |
| 35000HP-sodC-cat | 3 | 3 | ||||
| 192 | 7 | 35000HP | 2 | 2 | ||
| 35000HP-sodC-cat | 3 | 3 | ||||
a
Each volunteer was inoculated at two sites with the parent (35000HP) and at three sites with the mutant (35000HP-sodC-cat). Volunteers 186, 187, and 188 were inoculated in the first iteration, and volunteers 190, 191, and 192 were inoculated in the second iteration.