TABLE 1.
Effect of MAb 1C3 on oocyst development of P. gallinaceum in Aedes aegypti mosquitoesa
Treatment | No. of oocysts/gutb | Infectivity (%)c | No. infected/total no.d | Pe |
---|---|---|---|---|
PBS (−) cont.f | 1.68 | 100 | 14/19 | <1.000 |
Allosamidin (+) cont.g | 0.15 | 8.8 | 2/21 | <0.001 |
IgG2b ICh (20 μg) | 1.41 | 84 | 8/14 | <1.000 |
IgG2b IC (40 μg) | 1.56 | 92 | 13/23 | >0.100 |
1C3 (20 μg) | 0.22 | 13 | 3/14 | <0.010 |
1C3 (40 μg) | 0.12 | 7 | 2/26 | <0.001 |
These data are representative of two experiments with similar results.
Geometric mean.
Infectivity if expressed as the percentage of mean oocysts per gut relative to that of the control group.
Number of mosquitoes infected/total number of mosquitoes dissected.
P values were determined by the Mann-Whitney U test.
Negative control.
Positive control.
IC, isotype control.