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. 2025 Dec 11;34(1):45–64. doi: 10.4062/biomolther.2025.125

Table 2.

Summary of machine learning classifiers applied in medical imaging for diagnostic and risk stratification tasks

Classifier Data/Modality Task Sample size/Dataset Key performance References
RBF-SVM Clinical+Imaging Distinguish benign vs malignant 1,232 nodules from 724 patients ML model outperformed human experts; exact metrics in original paper Zhang et al., 2023b
CNN Ultrasound images Thyroid nodule detection 21,532 images from 5,842 patients AUROC: 98.51%; sensitivity: 93.5% (R-CNN) Xi et al., 2022
CNN Ultrasound, radiologist comparison Malignancy risk stratification Not specified in snippet Sensitivity: ~81.8%, specificity: ~86.1%, accuracy: ~85.1% Kim et al., 2025
CBIR MRI images (eye/orbit) Diagnostic accuracy enhancement 48 cases interpreted by 36 radiologists Accuracy improved from 55.9% to 70.6% with CBIR alone; further to 83.3% combined Rumberger et al., 2025
RBM Ultrasound features Unsupervised feature learning Various features across studies RBM listed among feature extraction methods (Wang et al., 2024