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. 2025 Aug 19;33(1):40–54. doi: 10.5551/jat.65441

Supplemental Table 5. Modified Poisson regression analysis of APOA-I and HDL-C/P ratio in 5-year risk of plaque progression and plaque incidence in participants without lipid-lowering medications, respectively.

Plaque Progression Plaque Incidence
RR (95% CI) P value RR (95% CI) P value
APOA-I (mg/dL)
<134.7 Ref Ref
134.7 - 150.4 1.09 (0.87 - 1.38) 0.452 1.20 (0.90 - 1.62) 0.216
≥ 150.5 0.99 (0.68 - 1.45) 0.957 1.10 (0.69 - 1.77) 0.686
HDL-C/P ratio
<44.8 Ref Ref
44.8 - 52.2 1.28 (1.03 - 1.58) 0.024 1.24 (0.97 - 1.59) 0.081
≥ 52.3 1.52 (1.09 - 2.12) 0.013 1.51 (1.05 - 2.17) 0.024

RRs (95% CI) were calculated by modified Poisson regression analysis, and all substantial models were adjusted for age (per 5 years), sex, BMI, diabetes, smoking, systolic blood pressure (per 10mmHg), anti-hypertensive medications, lipid-lowering medications, log-transformed high-sensitivity C-reactive protein levels, log-transformed triglyceride, low-density lipoprotein cholesterol (per 20mg/dL), and HDL particle size (per 0.4 nm).