Table 2. Correlation with desmosterol.
| Correlation Coefficient | p value | |
|---|---|---|
| T-Cho | 0.546 | <0.001 |
| LDL-C | 0.525 | <0.001 |
| Triglyceride | 0.270 | <0.001 |
| ALT | 0.196 | <0.01 |
| Ferritin | 0.168 | <0.05 |
| HOMA-R | 0.166 | <0.05 |
| Alb | 0.112 | 0.110 |
| AST | 0.095 | 0.163 |
| Weight | 0.056 | 0.418 |
| WBC | 0.021 | 0.768 |
| FBS | 0.006 | 0.930 |
| BUN | 0.002 | 0.973 |
| BMI | 0.016 | 0.816 |
| HDL-C | -0.005 | 0.940 |
| γ-GTP | -0.008 | 0.912 |
| ALP | -0.019 | 0.785 |
| Creatinine | -0.057 | 0.417 |
| HbA1c | -0.069 | 0.314 |
| Platelet count | -0.074 | 0.29 |
| Age | -0.162 | <0.05 |
Note: Correlation coefficient with desmosterol were analyzed by Pearson’s test. HOMA-R, Ferritin and HbA1c were completed with simple imputation (median imputation, 17.1%, 37/217, 0.9%, 2/217, and 1.8%, 4/217 respectively). In terms of HOMA-R, the data of insulin-treated patients (n = 5) were also dealt with as missing values. LDL-C and HDL-C were also completed with simple imputation (mean imputation, 1.4%, 3/217, 0.2%, 1/217, respectively).
Abbreviation: γ-GTP, gamma-glutamyl transpeptidase; AST, aspartate transaminase; ALT, alanine transaminase; BMI, body mass index; FBS, fasting blood sugar; HbA1c, glycated hemoglobin; HDL, High density lipoprotein; HOMA-R, homeostasis model assessment insulin resistance; LDL-C; Low density lipoprotein cholesterol; T-Cho, Total cholesterol