TABLE 1.

Infection with viable and viable plus heat-killed M. tuberculosis

Type of infection and no. of wk	No. of CFUa (log10) in:			Amt of lung cytokine mRNAa (units) for:
	Lung	Spleen	Liver	TNF-α	IL-6
Viable bacilli
1	3.7 ± 0.1	0	1.4 ± 1.2	63 ± 22	46 ± 10
2	5.2 ± 0.3	1.6 ± 1.5	1.9 ± 1.6	69 ± 30	174 ± 17
3	5.5 ± 0.1	3.9 ± 0.2	3.2 ± 0.6	144 ± 53	233 ± 33
4	6.0 ± 0.3	4.1 ± 0.1	2.6 ± 0.3	151 ± 51	161 ± 15
Viable + heat-killed bacilli
1	3.5 ± 0.4	0	1.8 ± 1.7	33 ± 5	46 ± 5
2	5.1 ± 0.2	0.9 ± 0.5	2.8 ± 0.8	111 ± 9	243 ± 25
3	5.5 ± 0.1	3.6 ± 0.2	3.2 ± 0.2	269 ± 24b	384 ± 37b
4	5.8 ± 0.2	3.9 ± 0.6	3.4 ± 0.2	132 ± 81	149 ± 27

^aNumber of mice per group per time point (n = 5).

^bP < 0.05 compared to infection with viable bacilli only.