TABLE 1.
Infection of HeLa-CEACAM cell lines with Opa deletion mutants
| Receptor type | Infection assay resulta with:
|
|||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| mBB
|
mBB ΔSV
|
mBB ΔHV-1
|
mBB ΔHV-2
|
mBB ΔHV-1+2
|
mII
|
mII ΔSV
|
mII ΔHV-1
|
mII ΔHV-2
|
||||||||||
| in | adh | in | adh | in | adh | in | adh | in | adh | in | adh | in | adh | in | adh | in | adh | |
| CEACAM3 | ++ | ++ | ++ | ++ | − | − | − | − | − | − | ++ | ++ | ++ | ++ | − | − | − | − |
| CEACAM6 | ++ | ++ | ++ | ++ | − | − | − | − | − | − | ++ | ++ | ++ | ++ | − | − | − | − |
| CEA | ++ | ++ | ++ | ++ | − | + | − | + | − | − | ++ | ++ | ++ | ++ | − | − | − | − |
a
Results of infection assays obtained by microscopic evaluation of invasion (in) and adherence (adh) of bacteria. ++ for CEACAM3, 10 to 15 bacteria per cell (in) or 10 to 15 bacteria per cell (adh); ++ for CEACAM6 and CEA, 4 to 8 bacteria per cell (in) or 40 to 50 bacteria per cell (adh);+, 15 to 20 bacteria per cell;−, 0 bacteria per cell (in) or 0 to 5 bacteria per cell (adh).