AD	Alzheimer’s disease
AAV	adeno-associated virus
BBB	blood–brain barrier
BDNF	brain-derived neurotrophic factor
CNS	central nervous system
CRISPR	clustered regularly interspaced short palindromic repeats
CSF	cerebrospinal fluid
CX3CL1	C-X3-C motif chemokine ligand 1
CX3CR1	C-X3-C motif chemokine receptor 1
DAM	disease-associated microglia
DCX	doublecortin
DG	dentate gyrus
EVs	extracellular vesicles
IFN-γ	interferon-gamma
IL-1β	interleukin-1 beta
IL-18	interleukin-18
iPSC	induced pluripotent stem cell
JAK/STAT1	janus kinase/signal transducer and activator of transcription 1
MCC950	nlrp3 inflammasome inhibitor mcc950
MRI	magnetic resonance imaging
NLRP3	nod-like receptor protein 3
NSAID	non-steroidal anti-inflammatory drug
NSPCs	neural stem and progenitor cells
PET	positron emission tomography
PSA-NCAM	polysialylated neural cell adhesion molecule
RNA-seq	RNA sequencing
SVZ	subventricular zone
TBI	traumatic brain injury
TNF-α	tumor necrosis factor-alpha
TSPO	translocator protein 18 kDa
Wnt	wingless-related integration site signaling pathway