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. 2026 Jan 1;15(1):317. doi: 10.3390/jcm15010317
ACE-I Angiotensin-Converting Enzyme Inhibitor
advSM Advanced Systemic Mastocytosis
AE Adverse Event
AKT Protein Kinase B
ARB Angiotensin Receptor Blocker
ALK Anaplastic Lymphoma Kinase
AXL AXL Receptor Tyrosine Kinase
BCR-ABL Fusion Oncoprotein Driving Chronic Myeloid Leukemia (CML)
BP Blood Pressure
B-RAF Serine/Threonine-Protein Kinase B-RAF
CBC Complete Blood Count
C-KIT Mast/Stem Cell Growth Factor Receptor
CML Chronic Myeloid Leukemia
CSF-1R Colony-Stimulating Factor 1 Receptor
CT Computed Tomography
DVT Deep Venous Thrombosis
EAP Expanded Access Program
EGFR Epidermal Growth Factor Receptor
ERK Extracellular Signal-Regulated Kinase
FDA U.S. Food and Drug Administration
FGFR Fibroblast Growth Factor Receptor
FLT3 FMS-Like Tyrosine Kinase 3
G-CSF Granulocyte Colony-Stimulating Factor
GI Gastrointestinal
GIST Gastrointestinal Stromal Tumor
HCC Hepatocellular Carcinoma
HER Human Epidermal Growth Factor Receptor
HF Heart Failure
HFSR Hand–Foot Skin Reaction
IFN-α Interferon-Alpha
KIT KIT Receptor Tyrosine Kinase
LFT/LFTs Liver Function Test / Liver Function Tests
LVEF Left Ventricular Ejection Fraction
MEK Mitogen-Activated Protein Kinase
MET MET (HGF) Receptor Tyrosine Kinase
mCRC Metastatic Colorectal Cancer
MRI Magnetic Resonance Imaging
mRCC Metastatic Renal Cell Carcinoma
NET Neuroendocrine Tumor
ORR Objective Response Rate / Overall Response Rate
OS Overall Survival
PDGFRα(A)/β(B) Platelet-Derived Growth Factor Receptors Alpha and Beta
PFS Progression-Free Survival
PI3K Phosphoinositide 3-Kinase
PK/PD Pharmacokinetics/Pharmacodynamics
pNET/pNETs Pancreatic Neuroendocrine Tumor(s)
RAS Rat Sarcoma Protein
RAF Rapidly Accelerated Fibrosarcoma Kinase
RCC Renal Cell Carcinoma
RET RET Receptor Tyrosine Kinase
R0 Complete Resection with Negative Margins
RFS Recurrence-Free Survival
ROS1 Proto-Oncogene Tyrosine-Protein Kinase ROS
SDH Succinate Dehydrogenase
TEAE Treatment-Emergent Adverse Event
TIE2 Angiogenesis Receptor Tyrosine Kinase
TKI/TKIs Tyrosine Kinase Inhibitor(s)
TIE2 Tunica Interna Endothelial Cell Kinase 2
TRKs Tropomyosin Receptor Tyrosine Kinases
TSH Thyroid-Stimulating Hormone
TTP Time to Progression
VEGF Vascular Endothelial Growth Factor
VEGFR1–3 Vascular Endothelial Growth Factor Receptors 1–3