RCT	randomized controlled trial
MDMA	3,4-methylenedioxymethamphetamine
LSD	lysergic acid diethylamide
PTSD	post-traumatic stress disorder
MD	major depression
AUD	alcohol use disorder
MDD	major depressive disorder
SUD	substance use disorder
BD	bipolar disorder
DSM	Diagnostic and Statistical Manual of Mental Disorders
ICD	International Classification of Diseases
PRISMA	Preferred Reporting Items for Systematic Reviews and Meta-Analyses
PICOS	Population, Intervention, Comparator, Outcomes, Study design
AMSTAR2	Assessment of Multiple Systematic Reviews 2
GRADE	Grading of Recommendations Assessment, Development and Evaluation
OR	odds ratio
RR	risk ratio
CI	confidence interval
SMD	standardized mean difference
ED50	effective dose for 50% of population
ED95	effective dose for 95% of population
MD	mean difference
SD	standard deviation
ECG	electrocardiogram
FDA	Food and Drug Administration
CBT	cognitive behavioral therapy
SSRIs	selective serotonin reuptake inhibitors
CANMAT	Canadian Network for Mood and Anxiety Treatments
CAPS	Clinician-Administered PTSD Scale
BDI	Beck Depression Inventory
SDS	Sheehan Disability Scale
PSQI	Pittsburgh Sleep Quality Index
DES	Dissociative Experiences Scale
ADR	adverse drug reaction
AE	adverse event