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. 2002 Apr;70(4):1724–1738. doi: 10.1128/IAI.70.4.1724-1738.2002

TABLE 1.

IC50s of capsular polysaccharides in the binding of vaccine-induced GBS IIIPS-specific antibodies to IIIPS in the fluid phase (RABA) and in the solid phase (III-HSA and IIIPS + mHSA ELISAs)a

Immunoassay IC50 (ng/ml) with indicated serum and inhibition
SHRS III
Reference serum 19
GBS IIIPS GBS III-HSA Pn14 PS GBS IIIPS GBS III-HSA Pn14 PS
GBS III RABA 175 215 10,000b NDc ND ND
III-HSA ELISA 38 38 10,000 215 375 NId
IIIPS + mHSA ELISA 3 3 1,000e 1 1 NI
a

Data are from Fig. 1 and 6 or not shown.

b

The IC40 is given.

c

ND, not done.

d

NI, no detectable inhibition.

e

The IC45 is given.