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Serum IgG responses to S. enterica serovar Typhimurium LPS and SOMPs and to rPspA. The data represent IgG antibody levels induced in mice orally immunized with χ8501(pYA3493) (vector control) and χ8501(pYA3494) (expressing rPspA) at the indicated weeks after immunization. ELISA and data analysis are described in Materials and Methods. Arrows indicate sublethal i.v. infection with S. pneumoniae WU2.
