TABLE 6.
Effect of parenteral challenge of B. mallei-vaccinated BALB/c mice
| Group | Immunogena | No. of mice | Challengeb
|
No. of survivorsc | |
|---|---|---|---|---|---|
| B. mallei strain | No. of cells | ||||
| I | HKGB15 | 5 | GB15.1-2 | 2.3 × 108 | 0 |
| IRGB15 | 4 | GB15.1-2 | 2.3 × 108 | 1 | |
| CapGB15 | 5 | GB15.1-2 | 2.3 × 108 | 0 | |
| II | IRGB15 | 5 | GB15.1-2 | 2.8 × 108 | 1 |
| IRGB15 | 5 | CapGB15 | 2.8 × 108 | 5 | |
| IRGB15 | 5 | CapGB15 | 6.5 × 108 | 4 | |
| Adjuvant | 5 | GB15.1-2 | 2.8 × 108 | 0 | |
a
Two vaccinations were given per mouse as stated in Materials and Methods.
b
Mice were challenged i.p. 3 to 4 weeks after the second vaccination.
c
Mice were observed for 21 days after the challenge.