TABLE 1.

Anti-MP antibody levels^a in the vaginal fluids of rats immunized i.v.g. and i.n. with MP or Sap and challenged or not with C. albicans^b

Immunizationc	Level of anti-MP antibodyd for group
	Immunized only			Immunized and challenged
	IgG	IgM	IgA	IgG	IgM	IgA
None	0.09	0.07	0.14	0.20	0.09	0.22
CT, i.n.	0.09	0.10	0.09	0.18	0.15	0.22
CT, i.v.g.	0.08	0.10	0.08	NDe	ND	ND
MP, i.n.	0.22	0.19	0.21	0.21	0.18	0.18
MP, i.v.g.	0.25	0.09	0.24	0.20	0.14	0.21
MP + CT, i.n.	0.34	0.11	0.34	0.89	0.48	0.64
MP + CT, i.v.g.	0.38	0.09	0.33	0.55	0.34	0.51
Sap, i.n.	0.14	0.10	0.16	0.23	0.22	0.24
Sap, i.v.g.	0.15	0.10	0.16	0.22	0.11	0.24
Sap + CT, i.n.	0.19	0.18	0.17	0.18	0.22	0.26
Sap + CT, i.v.g.	0.16	0.15	0.18	0.22	0.11	0.24

^aMeasured by ELISA on pools of vaginal washes from each rat (five per group) (diluted 1:2) taken at the end of the immunization protocol (day 28 since the first administration of the immunogen) and on day 7 after challenge.

^bChallenge: 10⁷ C. albicans cells in 0.1 ml.

^cSee the text for the protocol of immunization.

^dThe values are optical density readings at 405 nm. They are those of the experiment referred to in Fig. 1A.

^eND, not done.