Table 2.

Common exclusion criteria and circumstances in which people meeting exclusion criteria would become eligible (if any)

Criteria relating to:	Trials mentioning criteria (n, %)
Prior or concurrent malignancies	50/68, 74%
Exclude all	9/50, 18%
Include if disease-free 2 years	9/50, 18%
Include if disease-free 3 years	16/50, 32%
Include if disease-free 5 years	16/50, 32%
Pregnancy or breastfeeding	47/68, 69%
Exclude all	47/47, 100%
People of childbearing potential	47/68, 69%
Exclude all	0/47, 0%
Include if not pregnant or breastfeeding	10/47, 21%
Include if effective contraception used	37/47, 79%
CNS metastases	44/68, 65%
Exclude all metastases	18/44, 41%
Exclude all CNS metastases	4/44, 9%
Include if treated/asymptomatic	22/44, 50%
HIV	28/68, 41%
Exclude all	21/28, 75%
Include if undetectable viral load	7/28, 25%
Hepatitis B or C	25/68, 37%
Exclude all	8/25, 32%
Include if undetectable viral load	17/25, 68%