FIG. 1.

Effect of CPA treatment and bacterial infection on animal health over time. PBS-treated and CPA-treated mice were challenged with ≈1.6 × 10⁴ B. cepacia genomovar III strain C6433 or B. multivorans strain C1576. Animals were monitored daily for the duration of the experiment and assessed on a three-point system for ill health. Unhealthy animals (light bars) and healthy animals (dark bars) are shown for each day. The total number of animals studied decreased over time as animals were removed for analysis. Asterisks denote days on which animals were euthanatized due to extreme systemic illness. Arrows denote administration of either CPA or PBS.