TABLE 1.
BCC strains used in this study
| Strain | Strain typea | Source, locationb | BCESMc | cblAd | Status at day 16 in vivo |
|---|---|---|---|---|---|
| B. multivorans (genomovar II) | |||||
| C5393 | 03 | CF, Canada | − | − | Persistent |
| C3430 | 07 | CF, Canada | − | − | Cleared |
| C1576 | 10 | CF-e, UK | − | − | Persistent |
| C5274 | 12 | CF, Canada | − | − | Persistent |
| FC147 | 12 | CGD, USA | − | − | Persistent |
| C5568 | 19 | CF, Canada | − | − | Persistent |
| B. cepacia (genomovar III) | |||||
| C1257 | 01 | CF-e, USA | + | − | Cleared |
| C5424 | 02 | CF-e, Canada | + | + | Cleared |
| K56-2 | 02 | CF-e, Canada | + | + | Cleared |
| C6433 | 04 | CF-e, Canada | + | − | Cleared |
| Cep511 | 05 | CF-e, Australia | + | − | Cleared |
| C4455 | 06 | CF-e, Canada | + | − | Cleared |
| C1394 | 13 | CF-e, UK | + | − | Cleared |
| B. stabilis (genomovar IV) | |||||
| C7322 | 16 | CF, Canada | − | − | Cleared |
| B. vietnamiensis (genomovar V) | |||||
| FC811 | 08 | CF, USA | − | − | Persistent |
| B. cepacia (genomovar VI) | |||||
| Cep873 | 10 | CF, Canada | − | − | Persistent |
a
Strain type is the numerical randomly amplified polymorphic DNA type assigned previously to this fingerprint pattern (19).
b
CF, strain from a CF patient; CF-e, strain that has spread epidemically among patients with CF; CGD, infection of a chronic granulomatous disease patient; UK, United Kingdom; USA, United States.
c
BCESM, presence of B. cepacia epidemic strain marker (19).
d
cb1A, presence of cable pilus subunit gene (19).