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. 2002 May;70(5):2665–2669. doi: 10.1128/IAI.70.5.2665-2669.2002

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Copyright © 2002, American Society for Microbiology

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FIG. 4. — Impact of HdCDT on an in vitro model of angiogenesis. ECs and tubuli were visualized by staining for PECAM (CD31) (shown in red). In control (PBS-treated) wells long tubuli are formed (A). With 10² CPU (B) and 10⁴ CPU (C) of HdCDT per ml the tubuli are shorter and less branched. Increasing the concentration further to 10⁵ CPU HdCDT per ml (D) totally inhibits the formation of tubuli. The cell density of the fibroblast-like cells is decreased at high concentrations of HdCDT (D) compared to control (A).