TABLE 1.

Numbers of CFU in organs of IgG-treated C3^−/− mice 2 days after C. neoformans infection^a

Ascites fluid	No. of CFU (104)
	Lung	Liver	Spleen	Brain
NSO	180 ± 93b	7 ± 3.0	16.0 ± 13.0	0.08 ± 0.06
IgG1	27 ± 19c	20 ± 6.0c	1.7 ± 0.4c	0.30 ± 0.17c
IgG2a	66 ± 26c	20 ± 6.2c	2.0 ± 0.4c	0.09 ± 0.04
IgG2b	48 ± 27c	21 ± 8.0c	0.7 ± 0.4c	0.12 ± 0.07
IgG3	43 ± 33c	39 ± 10.0c	2.7 ± 1.0c	0.23 ± 0.10c

^aGroups of four mice were given either 1.0 mg of MAb or 1.0 ml of NSO ascites fluid 24 h prior to infection with 10⁶ CFU of C. neoformans.

^b1 standard deviation.

^cP < 0.05 versus NSO.