FIG. 2.
Susceptibility to IPA following T-cell-depleted allogeneic BM transplantation. Lethally irradiated C3H/HeJ mice had received transplants of ≥2 × 106 T-cell-depleted allogeneic BM cells from DBA/2 mice and were infected with A. fumigatus on days 3, 7, and 14 after transplantation as described in Materials and Methods. MST, median survival time (days). ∗, P < 0.05 (transplanted versus donor mice) according to Mann-Whitney U test. Chitin content (expressed as micrograms of glucosamine per pair of lungs) in the lungs of infected mice was determined 1 day after the last fungal inoculation. ∗, P < 0.05 (transplanted versus donor mice) according to ANOVA and Bonferroni's test.