Clearance of H. influenzae 24 h after infection. mBD-1−/− mice have significantly higher loads at all three doses than mBD-1+/+ mice, as indicated by asterisks (Mann-Whitney rank sum test, with P values for increasing doses of 0.015, 0.022, and 0.009, respectively). Symbols represent individual animals (▵, C57B1/6; ○, mBD-1+/+; •, mBD-1−/−); bars show group averages. The limit of detection for bacteria in this assay was 100 CFU per lung; lungs with fewer bacteria are therefore depicted as having 100 CFU.