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Circulating IL-18 during disseminated candidiasis. Groups of 10 TNF+/+ LT+/+ and TNF−/− LT−/− mice were injected i.v. with 105 C. albicans CFU. IL-18 concentrations in the serum of TNF+/+ LT+/+ (closed circles) and TNF−/− LT−/− (open triangles) mice were measured by enhanced chemiluminescence at various time points after infection (the experiment was performed twice, with a total of 10 animals per time point). Asterisk, P < 0.05
