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. 2025 Dec 22;9(1):191–213. doi: 10.1021/acsptsci.5c00707

6. CD73 Inhibition and PK Properties of 6-(Het)­aryl 7-Deazapurine 2′-Fluoroarabino Nucleoside 5′-O-Bisphosphonates (35A.5-7,12,17,23,28).

graphic file with name pt5c00707_0021.jpg

a

Cl: observed clearance.

b

t 1/2 stability in plasma.

c

fup: fraction unbound in human plasma. nt: not tested.