FIG. 2.

Enrichment for INH-resistant (INH-R) clones and clones containing DNA inserts after multiple rounds of selection in THP-1 cells. Individual colonies surviving the infection were picked from plates with kanamycin and tested for INH resistance by streaking on plates with and without INH. Colonies were also tested for the presence of a DNA insert by PCR analysis of heat-killed bacteria using primers flanking the site of insertion. Symbols: •, percentage of INH-resistant clones; ▪, percentage of clones with inserts.