FIG. 4.

MCP-1^−/− mice have enhanced osteolysis resulting from infection. The area of each lesion at the dental root apex was determined with a computer-assisted image analysis system at different times following exposure of the dental pulp and inoculation of bacteria. For each value the area at zero time representing the normal space between the root apex and bone was subtracted. The means ± standard errors based on five or six specimens are shown. WT, wild type.